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3 Treatment 149 13. Hayes, J. Transcriptional noise, plasticity, genetic networks; Ozbudak EM et al 2002 Nature Genet 31:69; Elowitz MB et al 2002 Science 297:1183; Rao C et al 2002 Nature [Lond] 420:231; Raser JM, OShea EK 2005 Science 309:2010; delay-induced oscillations in gene regula- tion: Bratsun D et al 2005 Proc Natl Acad Sci USA 102:14593; possible role Wnt in noise filtering in development: Arias AM, Hayward P 2006 Nature Rev Genet 7:34; noise in gene function: Maheshri N, Oshea EK 2007 Annu Rev Biophys Biomol Struct 36:413.

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2 1. The permutation matrix ensures that the larger elements are brought to the top of the system of linear equations. 2, the activity of Binnary was downregulated when co-expressed with Rac-B in Xenopus oocytes. The hypothesis behind Liapunov exponents is that there are parameter domains in which the distance between neigh- bouring solutions exhibits exponential growth in certain directions and exponential decay in other directions.

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MMWR 2002;51:2536. Meienberg O, Mumenthaler M, Karbowski K. 5, 24. Malis LI (1978) Intramedullary spinal cord tumours. Of these, approximately one-third were CD45-positive leukocytes (mean: 1,273 cells).

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